
彭英偉博士現為加拿大女皇大學(Queen’sUniversity)公共健康科學系終身教授,公共健康科學系生物統計碩士研究生項目主任,數學與統計系兼職教授,女皇大學癌癥研究所癌癥護理及流行病研究室的資深生物統計分析師,同時也是泛華統計協會加拿大分會現任主席。在主流統計學和醫學雜志上發表了120余篇論文,出版CRC/ChapmanHall專著1本,主持或參與加拿大自然科學與工程研究院(NSERC)和美國國立衛生研究院(NIH)等科研基金項目,擔任CanadianJournal of Statistics副主編,MathematicalReviews評論員,并擔任加拿大衛生研究院(CIHR)、加拿大自然科學與工程研究院(NSERC)等基金評審委員會成員。研究興趣和領域包括生存分析,癌癥研究中的治愈率模型,縱向數據分析,統計計算,因果分析方法等,與在加拿大,美國,中國,西班牙,臺灣等地的學者有廣泛的合作,已畢業的碩士和博士生多在美國和中國著名大學擔任教授或在知名公司和研究所從事統計分析和研究工作。
報告主題:統信大講堂|帶治愈率的長度偏差和區間刪失數據的一類新的似然估計方法
報告主題:Anew likelihood estimation method for length-biased andinterval-censored data with a cure fraction
摘要: Length-biaseddata, a special case of left-truncated data, assume that theincidence of the initial event follows a homogeneous Poisson process.I will introduce length-biased and interval-censored data with a curefraction arising from an early-onset diabetes mellitus study and anew method to analyze such data in this talk. The Cox proportionalhazards model for the survival time of the susceptible individualsand the logistic regression model for the probability of beingsusceptible are employed to model the data. We construct the fulllikelihood function and obtain the nonparametric maximum likelihoodestimates of the regression parameters by employing the EM algorithm.The large sample properties of the estimates are established. Theperformance of the method is assessed by simulations. The proposedmodel and method are applied to the data from the early-onsetdiabetes mellitus study. This is collaborative work with Chyong-MeiChen, Hsin-Jen Chen, and Pao-Sheng Shen.